KATHRYN HANLEY, PI

                           

    NMSU: Biology

                                                                 


  
     


 
 

Kathryn A. Hanley
  • Assistant Professor of Biology
    New Mexico State University
  • Adjunct Assistant Professor
    University of New Mexico School of Medicine
     

    Address: W361, Chemistry Building
    New Mexico State University
    Las Cruces, NM 88003-8001
    Phone: 505 646 4583 (Office)
                   505 646 4791 (Lab)

    E mail: khanley@nmsu.edu

 Web: http://biology-web.nmsu.edu/hanley
 Lab page: http://biology-web.nmsu.edu/hanley/

       Publications

       Teaching



 

 

 

 

 

Link to Kathryn Hanley's KRWG interview (Feb, 2009)

PUBLICATIONS

Book chapter

Origin and Evolution of Viruses

Peer-reviewed (Journal Article)

*   Vasilakis, N., E. Deardoff, J.L. Kenney, S.R. Rossi, K.A. Hanley, S.C. Weaver. 2009.
Mosquitoes put the brake on evolution: experimental evolution reveals slower
mutation accumulation in mosquito cells than vertebrate cells. submitted to
PLoS Pathogens.

* Joseph, S.B., K.A. Hanley, L. Chao, C.L. Burch. 2009. Coinfection rates in ?6
bacteriophage are enhanced by virus-induced changes in host cells. Evolutionary
Applications. Epub ahead of print.

* Pepin, K.M. and Hanley K.A. 2008. Density-dependent competitive suppression of sylvatic dengue virus by endemic dengue virus in cultured mosquito cells. submitted to Vector Borne and Zoonotic Diseases.

*       Vasilakis, N., E.B. Fokam, C.T.Hanson, E. Weinberg, A.A. Sall, S. S. Whitehead, K.A. Hanley, S.C. Weaver. 2008. Genetic and phenotypic characterization of sylvatic dengue strains. submitted to Virology.       

*       Hanley, K.A., J.T. Nelson, E. E. Schirtzinger, S.S. Whitehead, C.T. Hanson. 2008. Superior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virus. BMC Ecology 8:1.[PDF]

*       Pepin, K.M., K. Lambeth, K.A. Hanley. 2008. Asymmetric competitive suppression between strains of dengue virus. BMC Microbiology 8:28.[PDF]

*       Blaney, J.E., Jr., N. Sathe, C.T. Hanson. L. Goddard, T.A. Romero, K.A. Hanley, B.R. Murphy, S.S. Whitehead. 2008. Dengue virus type 3 vaccine candidates generated by introduction of deletions in the 3’ untranslated region (UTR) or exchange of the DENV3 3’ UTR with that of DENV4. Vaccine 26:817-28.

*       Vasilakos, N., E. J. Shell, E.B. Fokam, P.W. Mason, K.A. Hanley, D.M. Estes, and S.C. Weaver. 2006. Potential of ancestral sylvatic dengue-2 viruses to re-emerge. Virology 358, 402-412.[PDF]

*       T. A. Romero, E. Tumban, J. Jun, W.B.Lott, and K.A. Hanley. 2006. Secondary structure of dengue virus 4 3' untranslated region: Impact of deletion and substitution mutations. Journal of General Virology 87, 3291-3296. [PDF]

*       Hanley, K.A., L.B. Goddard, L.E. Gilmore, T.W. Scott, J. Speicher, B.R. Murphy, A. G. Pletnev. 2005. Infectivity of West Nile/Dengue chimeric viruses for West Nile and Dengue mosquito vectors. Vector-Borne and Zoonotic Diseases 5: 1-10.[PDF]

*       Blaney, Jr., J.E., C.T. Hanson, C. Y. Firestone, K.A. Hanley, B.R. Murphy, S.S. Whitehead. 2004. Genetically modified, live attenuated dengue virus type 3 vaccine candidates. The American Journal of Tropical Medicine and Hygiene 71: 811-821. [PDF]

*       Blaney, J.E., Jr., C.T. Hanson, K.A. Hanley, B.R. Murphy and S. W. Whitehead. 2004. Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2. Biomed Central Infectious Diseases 4: 39-49. [PDF]

*       Hanley, K.A., L.R. Manlucu, G.G. Manipon, C.T. Hanson, S.S. Whitehead, B.R. Murphy, J.E. Blaney Jr. 2004. Introduction of mutations into the non-structural genes or 3’ untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity. Vaccine 22:3440-3448.

*       Burch, C.L., P.E. Turner, and K.A. Hanley. 2003. Patterns of epistasis in RNA viruses: a review of the evidence from vaccine design. Journal of Evolutionary Biology 16:1223-1235.

*       Whitehead, S.S., K.A. Hanley, J.E. Blaney Jr., L.E. Gilmore, W.R. Elkins, and B.R. Murphy. 2003. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice and rhesus monkeys. Vaccine 21:4307-4316.

*       Hanley, K.A., L.R. Manlucu, L.E. Gilmore, J.E. Blaney Jr., C. T. Hanson, B.R. Murphy and S.S. Whitehead. 2003. A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4. Virology 312: 222-232.

*       Whitehead, S.S., B. Falgout, K.A. Hanley, J.E. Blaney Jr., L. Markoff, and B.R. Murphy. 2003. A live attenuated dengue virus type 1 vaccine candidate with a 30 nucleotide deletion in the 3’ untranslated region is highly attenuated and immunogenic in monkeys. Journal of Virology 77:1653-1657.

*       Hanley, K.A., J.J. Lee, J.E. Blaney, Jr., B.R. Murphy, and S.S. Whitehead. 2002. Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 confers temperature-sensitive, host-range and mouse attenuation phenotypes. Journal of Virology 76: 525-531.

*       Hanley, K.A. and J.A. Stamps. 2002. Does corticosterone mediate bidirectional interactions between social behaviour and blood parasites in juvenile black iguanas, Ctenosaura similis? Animal Behaviour 63: 311-322.

*       Troyer, J. M.1, K.A. Hanley1, S.S. Whitehead, D. Strickman, R.A. Karron, A. P. Durbin, and B. R. Murphy. 2001. A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes. The American Journal of Tropical Medicine and Hygiene 65:414-419. 1Equal contribution by first two authors.

*       Pletnev, A.G., M. Bray, K.A. Hanley, J. Speicher and R. Elkins. 2001. Tick-borne Langat/mosquito-borne Dengue flavivirus chimera, a candidate live-attenuated vaccine for protection against disease caused by members of the tick-borne encephalitis virus complex: evaluation in rhesus monkeys and mosquitoes. Journal of Virology 75: 8259-8267. [PDF]

*       Chao, L., K.A. Hanley, C. L. Burch, C. Dahlberg, and P.E. Turner. 2000. Kin selection and the evolution of virulence in parasites: Making hard and soft choices. Quarterly Review of Biology 75:261-275. [PDF]

*       Schall, J.J., H. R. Prendiville, and K.A. Hanley. 2000. Prevalence of the tick, Ixodes pacificus, on western fence lizards, Sceloporus occidentalis: Trends by gender, size, season, site and mite infestation. Journal of Herpetology 34:160-163.

*       K.A. Hanley, M.L. Elliott, and J.A. Stamps. 1999. Chemical recognition of familiar versus unfamiliar conspecifics by juvenile black iguanas, Ctenosaura similis. Ethology 105: 641-650.

*       Turner, P.E., C. L. Burch, K.A. Hanley, and L. Chao. 1999. Hybrid frequencies confirm limit to coinfection in the RNA bacteriophage Phi 6. Journal of Virology 73: 2420-2424. [PDF]

*       Hanley, K.A., K.R. Petren, and T.J. Case. 1998. An experimental investigation of the competitive displacement of a native gecko by an invading gecko: no role for parasites. Oecologia 115: 196-205.

*       Hanley, K.A., R.N. Fisher, and T.J. Case. 1995. Higher mite infestations in sexual geckos than their asexual congeners. Evolution 49(3): 418-436.

*       Hanley, K.A., D.M. Vollmer, and T.J. Case. 1995. The distribution and prevalence of helminths, coccidia and blood parasites in two competing species of gecko: implications for apparent competition. Oecologia 102: 220-229.

*       Radtkey, R.R., S. Donnellan, R.N. Fisher, C. Moritz, K.A. Hanley, and T.J. Case. 1995. When species collide: the origin and spread of an asexual gecko species. Proceedings of the Royal Society of London (Biology) 259:145-152.

*       Upton, S.J., K.A. Hanley, and T.J. Case. 1994. Eimeria frenatus sp. n. and Eimeriarochalimai (Apicomplexa: Eimeriidae) from Hemidactylus frenatus (Sauria:Gekkonidae) in Hawaii. Transactions of the American Microscopical Society113(3): 390-394.

*       Hanley, K.A., D.T. Bolger, and T.J. Case. 1994. Comparative ecology of sexual and asexual gecko congeners (Lepidodactylus) in French Polynesia. Evolutionary Ecology 8: 438-454. Upton, S.J., K.A. Hanley, T.J. Case, and C.T. McCallister. 1991. Description of Isospora schlegeli (Apicomplexa: Eimeriidae) from gekkonid lizards in the South Pacific. Canadian Journal of Zoology 69: 3108-3110 [PDF]

Teaching

  • Spring 2007  BIOL 475             Virology - SYLLABUS
     
  • Spring 2008 BIOL 101              Human Biology
     
  • Fall 2006   BIOL 450/550         Biology of Emerging Infectious Diseases -  SYLLABUS                      

Updated February, 2008