bio
490: neurobiology
dR.
sERRANO
Assignment
#1 (60 pts) due date: Feb 3
Edited 01/17/04
This assignment
is designed to acquaint you with databases, journals and
literature
about Neuroscience both on the Internet and at NMSU.
Instructions.
- PLEASE
SUBMIT ALL ASSIGNMENTS TYPED AND
SINGLE SPACED.
- NUMBER
ALL PAGES.
- DO NOT TYPE YOUR
NAME, INSTEAD,
INCLUDE THE LAST FOUR DIGITS
OF YOUR SOCIAL SECURITY NUMBER ON ALL
PAGES.
- BE BRIEF AND TO
THE POINT,.
Enjoy!
A. INTERNET
NEUROSCIENCE SEARCHES (45 pts)
1. (10 pts)
Visit
the Society for Neuroscience on
the
Net at http://www.sfn.org/
and complete the following assignments:
- Find the Journal
of
Neuroscience on line. Browse the issues. Select 3 abstracts
and download them. Submit the abstracts with a brief
(one paragraph) explanation of why you downloaded these articles.
- Visit the Brain
Briefings
Site http://www.sfn.org/briefings/.
List the five articles that interestes you the most and briefly
(in one paragraph) explain why these topics caught your eye.
2. (10 pts) Visit the NIH
site at http://www.nih.gov.
- What is NIH?
Visit one
of the institutes and report on the kinds of neuroscience research that
it funds. Why did you choose this institute?
- What is the NIH roadmap
Initiative http://nihroadmap.nih.gov/ ?
Which Pathway to Discovery interests
you
the most?
- Visit the CRISP
database http://crisp.cit.nih.gov/
.
- Use the query form to find grants
from NIH that are funded in New Mexico. How many hits did you get for
2004?. for 2000?
- Submit
three abstracts with a brief (2-3 sentences)
explanation
of why you downloaded these articles.
- Visit the AWARDS date page http://grants1.nih.gov/grants/award/awardtr.htm
and look under /current
data/rankings/.
- in 2002, which state received the
most NIH money? how much? How does NM rank?
- Which institution received the most
NIH money? How does NMSU rank?
3. (5 pts) Visit Neuroinformatics:
the Human Brain Project: (http://www.nimh.nih.gov/neuroinformatics/index.cfm)
- What is NCBI?
be sure to visit the site map http://www.ncbi.nlm.nih.gov/Sitemap/index.html
- Find GenBank
on
the NCBI home page and answer the following::
- What is GenBank?
- Select Nucleotide from the drop
down menu and search the nucleotide data base for ONE of the following : nestin / potassium
channel
/ myelin How many postings
did you find?
- Download a listing from your GENBANK
search that is interesting to you. What information does it contain?
- Visit
the Genes and Diseases site at NCBI.
(follow the link from the site map) Which category has the most
diseases? Follow a link of interest under Nervous System?
which did you choose and why?
5.
(3 pts) Visit
Pubmed
http://www4.ncbi.nlm.nih.gov/PubMed/
from NCBI Home. What is posted on this site? How many
articles do
you find if you query with the word "
neuron"? "cell"?
"hypothesis"? "brain"?
6. (5 pts)
Visit the
Clinical Trials website by
following
the link from the
PubMed
home on the left side of the page.
- What is the website for?
- Go
to Focused
Search
- What is a phase 1 clinical
trial? phase 2? phase 3?
- Find two studies under nervous
system
diseases recruiting in New Mexico. Who is sponsoring or
supporting the studies?. What are the responsibilities of the study
sponsors?
7. (4 pts)
Visit the Medline drug information site:
http://www.nlm.nih.gov/medlineplus/.
What information is posted about drugs on this site? What are potential
side effects for Prozac? for aspirin?
8. (2 pts)
Visit
the site http://jaxmice.jax.org/index.html
What
does this company sell? Go to Research models under JAX Mice Library. What types
of models are listed under Neurobiology?
B. NMSU LIBRARY
SEARCHES (15 pts)
1. (8 pts) Go to http://lib.nmsu.edu:80/article.html
on the NMSU library home page.
- List five electronic databases that
are
available on the internet.
- What is the link for the NMSU
electronic journals? They are on a library web page but you will
need to search to find this very important link.
- Go to the
LANL SciSearch database.
- Search the 1993 Sci Search (you
will need to select the year and database on the search menu) database
for papers using keywords human
AND brain.
How many papers did you find?
- Complete the same search for 1997
and 2002
and compare with 1993.
- Repeat B131 and B132 for for neuron .
- List the
titles and abstracts of three papers from SciSearch
and explain (briefly), why they interested you. Are they available in
our
library?
5. (4 pts) Find
the Neuroscience
section(s) of the library. Under what call numbers are Neuro
books
shelved? List the titles of three books that catch your eye. Find the Neuroscience
journals in the library. What are the call numbers? List the
titles
of three journals.
7. (3 pts) How
do
you get an article that is not in the library? How long does it usually
take? How
much does the library charge to xerox a page?